Pan-cancer analysis reveals tumor-associated macrophage communication in the tumor microenvironment

Pan-cancer analysis reveals tumor-associated macrophage communication in the tumor microenvironment

Abstract Background Tumor-associated macrophages (TAMs) are abundant in the tumor microenvironment (TME). However, their contribution to the immunosuppressive status of the TME remains unclear. Methods We integrated single-cell sequencing and transcriptome data from different tumor types to uncover...

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Bibliographic Details
Main Authors: Linbang Wang, Tao He, Jingkun Liu, Jiaojiao Tai, Bing Wang, Zhiyu Chen, Zhengxue Quan
Format: Article
Language:English
Published: BMC 2021-05-01
Series:Experimental Hematology & Oncology
Subjects:
Tumor-associated macrophages
Tumor microenvironment
Intercellular communication
FLI1
Online Access:https://doi.org/10.1186/s40164-021-00226-1

Internet

https://doi.org/10.1186/s40164-021-00226-1

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