Viperin, an IFN-Stimulated Protein, Delays Rotavirus Release by Inhibiting Non-Structural Protein 4 (NSP4)-Induced Intrinsic Apoptosis

Viperin, an IFN-Stimulated Protein, Delays Rotavirus Release by Inhibiting Non-Structural Protein 4 (NSP4)-Induced Intrinsic Apoptosis

Viral infections lead to expeditious activation of the host’s innate immune responses, most importantly the interferon (IFN) response, which manifests a network of interferon-stimulated genes (ISGs) that constrain escalating virus replication by fashioning an ill-disposed environment. Interestingly,...

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Bibliographic Details
Main Authors: Rakesh Sarkar, Satabdi Nandi, Mahadeb Lo, Animesh Gope, Mamta Chawla-Sarkar
Format: Article
Language:English
Published: MDPI AG 2021-07-01
Series:Viruses
Subjects:
rotavirus
interferon stimulated genes (ISGs)
viperin
non-structural protein 4 (NSP4)
apoptosis
Online Access:https://www.mdpi.com/1999-4915/13/7/1324

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https://www.mdpi.com/1999-4915/13/7/1324

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