Association between promoter -1607 polymorphism of <it>MMP1 </it>and Lumbar Disc Disease in Southern Chinese

<p>Abstract</p> <p>Background</p> <p>Matrix metalloproteinases (MMPs) are involved in the degradation of the extracellular matrix of the intervertebral disc. A SNP for guanine insertion/deletion (G/D), the -1607 promoter polymorphism, of the <it>MMP1 </it>ge...

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Main Authors: Leong John CY, Yip Shea-Ping, Luk Keith DK, Fan Bao-Jian, Kao Patrick YP, Karppinen Jaro, Ho Daniel WH, Song You-Qiang, Cheah Kathryn SE, Sham Pak, Chan Danny, Cheung Kenneth MC
Format: Article
Language:English
Published: BMC 2008-04-01
Series:BMC Medical Genetics
Online Access:http://www.biomedcentral.com/1471-2350/9/38