Persistent Basophilia May Suggest an “Accelerated Phase” in the Evolution of CALR-Positive Primary Myelofibrosis Toward Acute Myeloid Leukemia

Persistent Basophilia May Suggest an “Accelerated Phase” in the Evolution of CALR-Positive Primary Myelofibrosis Toward Acute Myeloid Leukemia

Basophils are white blood cells that play an important role in the human immune system. These cells physiologically increase in number in immune response to certain allergies, chronic inflammation, and parasitic infections. Basophils are also a significant indicator for the presence of certain malig...

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Bibliographic Details
Main Authors: Jerome Dobrowolski, Sergiu Pasca, Patric Teodorescu, Cristina Selicean, Ioana Rus, Mihnea Zdrenghea, Anca Bojan, Adrian Trifa, Bogdan Fetica, Bobe Petrushev, Ana-Maria Rosu, Ioana Berindan-Neagoe, Ciprian Tomuleasa, Delia Dima
Format: Article
Language:English
Published: Frontiers Media S.A. 2019-09-01
Series:Frontiers in Oncology
Subjects:
primary myelofibrosis
basophilia
leukemic transformation
accelerated phase
clinical prognosis
Online Access:https://www.frontiersin.org/article/10.3389/fonc.2019.00872/full

Internet

https://www.frontiersin.org/article/10.3389/fonc.2019.00872/full

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