Drug-target interactions prediction using marginalized denoising model on heterogeneous networks

Drug-target interactions prediction using marginalized denoising model on heterogeneous networks

Abstract Background Drugs achieve pharmacological functions by acting on target proteins. Identifying interactions between drugs and target proteins is an essential task in old drug repositioning and new drug discovery. To recommend new drug candidates and reposition existing drugs, computational ap...

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Bibliographic Details
Main Authors: Chunyan Tang, Cheng Zhong, Danyang Chen, Jianyi Wang
Format: Article
Language:English
Published: BMC 2020-07-01
Series:BMC Bioinformatics
Subjects:
Drug-target interaction
Marginalized denoising model
Drug discovery prediction
Drug repositioning prediction
Online Access:http://link.springer.com/article/10.1186/s12859-020-03662-8

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http://link.springer.com/article/10.1186/s12859-020-03662-8

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