AMPK Promotes Xenophagy through Priming of Autophagic Kinases upon Detection of Bacterial Outer Membrane Vesicles

AMPK Promotes Xenophagy through Priming of Autophagic Kinases upon Detection of Bacterial Outer Membrane Vesicles

Summary: The autophagy pathway is an essential facet of the innate immune response, capable of rapidly targeting intracellular bacteria. However, the initial signaling regulating autophagy induction in response to pathogens remains largely unclear. Here, we report that AMPK, an upstream activator of...

Full description

Bibliographic Details
Main Authors: Truc T. Losier, Mercy Akuma, Olivia C. McKee-Muir, Nicholas D. LeBlond, Yujin Suk, Reham M. Alsaadi, Zhihao Guo, Ryan Reshke, Subash Sad, François-Xavier Campbell-Valois, Derrick J. Gibbings, Morgan D. Fullerton, Ryan C. Russell
Format: Article
Language:English
Published: Elsevier 2019-02-01
Series:Cell Reports
Online Access:http://www.sciencedirect.com/science/article/pii/S2211124719300919

Internet

http://www.sciencedirect.com/science/article/pii/S2211124719300919

Similar Items