Thrombin generation by activated factor VII on platelet activated by different agonists. Extending the cell-based model of hemostasis

<p>Abstract</p> <p>Background</p> <p>Platelet activation is crucial in normal hemostasis. Using a clotting system free of external tissue factor, we investigated whether activated Factor VII in combination with platelet agonists increased thrombin generation (TG) in vit...

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Bibliographic Details
Main Authors: Herrera Maria, Scazziota Alejandra, Altman Raul, Gonzalez Claudio
Format: Article
Language:English
Published: BMC 2006-04-01
Series:Thrombosis Journal
Online Access:http://www.thrombosisjournal.com/content/4/1/5