Robust hematopoietic specification requires the ubiquitous Sp1 and Sp3 transcription factors

Robust hematopoietic specification requires the ubiquitous Sp1 and Sp3 transcription factors

Abstract Background Both tissue-specific and ubiquitously expressed transcription factors, such as Sp-family members, are required for correct development. However, the molecular details of how ubiquitous factors are involved in programming tissue-specific chromatin and thus participate in developme...

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Bibliographic Details
Main Authors: Jane Gilmour, Leigh O’Connor, Christopher P. Middleton, Peter Keane, Nynke Gillemans, Jean-Baptiste Cazier, Sjaak Philipsen, Constanze Bonifer
Format: Article
Language:English
Published: BMC 2019-06-01
Series:Epigenetics & Chromatin
Subjects:
Blood cell development
ATAC-seq
Single-cell RNA-seq
Embryonic development
Differentiation trajectories
Transcription factor cooperation
Online Access:http://link.springer.com/article/10.1186/s13072-019-0282-9

Internet

http://link.springer.com/article/10.1186/s13072-019-0282-9

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