Effect of Sample Preparation and Chromatographic Conditions on Background Signal

The HPLC-UV method is widely used for quantitative analysis of drug substances found in biological samples obtained in pharmacokinetics studies, bioequivalence studies, or during therapeutic drug monitoring. The main limitation is associated with a significant background effect of biological matrixe...

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Bibliographic Details
Main Authors: V. M. Kosman, M. V. Karlina, O. N. Pozharitskaya
Format: Article
Language:Russian
Published: OOO “Vashe Tsifrovoe Izdatelstvo” 2020-06-01
Series:Ведомости Научного центра экспертизы средств медицинского применения
Subjects:
Online Access:https://www.vedomostincesmp.ru/jour/article/view/292