Inhibition of ZEB1-AS1 confers cisplatin sensitivity in breast cancer by promoting microRNA-129-5p-dependent ZEB1 downregulation

Inhibition of ZEB1-AS1 confers cisplatin sensitivity in breast cancer by promoting microRNA-129-5p-dependent ZEB1 downregulation

Abstract Background Breast cancer is the leading cause of cancer-related mortality in women worldwide. Long non-coding RNAs (lncRNAs) are of critical importance in tumor drug resistance. Herein, this study aims to determine the roles of lncRNA ZEB1-AS1 in drug resistance of breast cancer involving m...

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Bibliographic Details
Main Authors: Jin Gao, Yuan Yuan, Lili Zhang, Shaorong Yu, Jianwei Lu, Jifeng Feng, Sainan Hu
Format: Article
Language:English
Published: BMC 2020-03-01
Series:Cancer Cell International
Subjects:
Long non-coding RNA ZEB1-AS1
ZEB1-AS1/miR-129-5p/ZEB1 signaling pathway
Drug resistance
Breast cancer
Online Access:http://link.springer.com/article/10.1186/s12935-020-1164-8

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http://link.springer.com/article/10.1186/s12935-020-1164-8

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