Involvement of µ-opioid Receptors and κ-opioid Receptors in Itch-related Scratching Behaviour of Imiquimod-induced Psoriasis-like Dermatitis in Mice

Involvement of µ-opioid Receptors and κ-opioid Receptors in Itch-related Scratching Behaviour of Imiquimod-induced Psoriasis-like Dermatitis in Mice

The pathogenesis of psoriatic itch is poorly understood. The aim of this study was to investigate the involvement of opioid receptors in scratching behaviour of imiquimod-induced psoriasis-like dermatitis model mice. Topical application of 5% imiquimod cream to the rostral back skin of mice induced...

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Bibliographic Details
Main Authors: Nobuaki Takahashi, Mitsutoshi Tominaga, Ryohei Kosaka, Yayoi Kamata, Yoshie Umehara, Hironori Matsuda, Azumi Sakaguchi, Hideoki Ogawa, Kenji Takamori
Format: Article
Language:English
Published: Society for Publication of Acta Dermato-Venereologica 2017-06-01
Series:Acta Dermato-Venereologica
Subjects:
imiquimod
itch
opioidreceptor
psoriasis
Online Access: https://www.medicaljournals.se/acta/content/html/10.2340/00015555-2704

Internet

https://www.medicaljournals.se/acta/content/html/10.2340/00015555-2704

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