Toxoplasma Uses GRA16 To Upregulate Host c-Myc

The proto-oncogene c-Myc plays a crucial role in the growth and division of many animal cells. Previous studies have identified an active upregulation of c-Myc by Toxoplasma tachyzoites, suggesting the existence of one or more exported “effector” proteins. The identity of such an effector, however,...

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Bibliographic Details
Main Authors: Michael W. Panas, John C. Boothroyd
Format: Article
Language:English
Published: American Society for Microbiology 2020-06-01
Series:mSphere
Subjects:
Online Access:https://doi.org/10.1128/mSphere.00402-20