Role of the NLRP3 inflammasome in cancer

Role of the NLRP3 inflammasome in cancer

Abstract Inflammasomes are large intracellular multi-protein signalling complexes that are formed in the cytosolic compartment as an inflammatory immune response to endogenous danger signals. The formation of the inflammasome enables activation of an inflammatory protease caspase-1, pyroptosis initi...

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Bibliographic Details
Main Authors: Maryam Moossavi, Negin Parsamanesh, Afsane Bahrami, Stephen L. Atkin, Amirhossein Sahebkar
Format: Article
Language:English
Published: BMC 2018-11-01
Series:Molecular Cancer
Subjects:
Nod-like receptor protein 3
Caspase-1
Interleukin-1β
Apoptosis-associated speck-like protein
Online Access:http://link.springer.com/article/10.1186/s12943-018-0900-3

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http://link.springer.com/article/10.1186/s12943-018-0900-3

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