Role of the NLRP3 inflammasome in cancer
Abstract Inflammasomes are large intracellular multi-protein signalling complexes that are formed in the cytosolic compartment as an inflammatory immune response to endogenous danger signals. The formation of the inflammasome enables activation of an inflammatory protease caspase-1, pyroptosis initi...
Main Authors: | , , , , |
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Format: | Article |
Language: | English |
Published: |
BMC
2018-11-01
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Series: | Molecular Cancer |
Subjects: | |
Online Access: | http://link.springer.com/article/10.1186/s12943-018-0900-3 |