The Promise of Lung Organoids for Growth and Investigation of Pneumocystis Species

The Promise of Lung Organoids for Growth and Investigation of Pneumocystis Species

Pneumocystis species (spp.) are host-obligate fungal parasites that colonize and propagate almost exclusively in the alveolar lumen within the lungs of mammals where they can cause a lethal pneumonia. The emergence of this pneumonia in non-HIV infected persons caused by Pneumocystis jirovecii (PjP),...

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Bibliographic Details
Main Authors: Nikeya Tisdale-Macioce, Jenna Green, Anne-Karina T. Perl, Alan Ashbaugh, Nathan P. Wiederhold, Thomas F. Patterson, Melanie T. Cushion
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-09-01
Series:Frontiers in Fungal Biology
Subjects:
Pneumocystis pneumonia
lung organoids
opportunistic fungal pathogen
immunosuppressed hosts
Pneumocytis species
Online Access:https://www.frontiersin.org/articles/10.3389/ffunb.2021.740845/full

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https://www.frontiersin.org/articles/10.3389/ffunb.2021.740845/full

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