Impact of Genetic Variation in TLR4 3′UTR on NSCLC Genetic Susceptibility

Toll-like receptors (TLRs) are expressed not only in immune cells but also in a variety of tumor cells. Single-nucleotide polymorphisms (SNPs) located in the TLRs’ promoter or the 3′ untranslated region may affect gene expression by affecting the activity of the promoter or regulating the binding of...

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Bibliographic Details
Main Authors: Hongjiao Wu, Hui Gao, Ang Li, Yuning Xie, Zhenxian Jia, Zhenbang Yang, Hongmei Zhang, Zhi Zhang, Xuemei Zhang
Format: Article
Language:English
Published: Hindawi Limited 2020-01-01
Series:Journal of Oncology
Online Access:http://dx.doi.org/10.1155/2020/7593143