2D- and 3D-cultures of human trabecular meshwork cells: A preliminary assessment of an in vitro model for glaucoma study.

A physiologically relevant in vitro human-based model could be the 'gold standard' to clarify the pathological steps involved in glaucoma onset. In this regard, human 3D cultures may represent an excellent starting point to achieve this goal. Indeed, the 3D matrix allows to re-create the i...

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Bibliographic Details
Main Authors: Stefania Vernazza, Sara Tirendi, Sonia Scarfì, Mario Passalacqua, Francesco Oddone, Carlo Enrico Traverso, Ilaria Rizzato, Anna Maria Bassi, Sergio Claudio Saccà
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2019-01-01
Series:PLoS ONE
Online Access:https://doi.org/10.1371/journal.pone.0221942