Bioactive Mimetics of Conotoxins and other Venom Peptides

Ziconotide (Prialt®), a synthetic version of the peptide ω-conotoxin MVIIA found in the venom of a fish-hunting marine cone snail Conus magnus, is one of very few drugs effective in the treatment of intractable chronic pain. However, its intrathecal mode of delivery and narrow therapeutic window cau...

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Bibliographic Details
Main Authors: Peter J. Duggan, Kellie L. Tuck
Format: Article
Language:English
Published: MDPI AG 2015-10-01
Series:Toxins
Subjects:
Online Access:http://www.mdpi.com/2072-6651/7/10/4175