Role of endothelial AADC in cardiac synthesis of serotonin and nitrates accumulation.

Role of endothelial AADC in cardiac synthesis of serotonin and nitrates accumulation.

Serotonin (5-HT) regulates different cardiac functions by acting directly on cardiomyocytes, fibroblasts and endothelial cells. Today, it is widely accepted that activated platelets represent a major source of 5-HT. In contrast, a supposed production of 5-HT in the heart is still controversial. To a...

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Main Authors: Charlotte Rouzaud-Laborde, Naïma Hanoun, Ipek Baysal, Jean-Simon Rech, Céline Mias, Denis Calise, Pierre Sicard, Céline Frugier, Marie-Helène Seguelas, Angelo Parini, Nathalie Pizzinat
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2012-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3400593?pdf=render

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http://europepmc.org/articles/PMC3400593?pdf=render

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