0.9% saline versus Plasma-Lyte as initial fluid in children with diabetic ketoacidosis (SPinK trial): a double-blind randomized controlled trial

0.9% saline versus Plasma-Lyte as initial fluid in children with diabetic ketoacidosis (SPinK trial): a double-blind randomized controlled trial

Abstract Background Acute kidney injury (AKI) is an important complication encountered during the course of diabetic ketoacidosis (DKA). Plasma-Lyte with lower chloride concentration than saline has been shown to be associated with reduced incidence of AKI in adults with septic shock. No study has c...

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Bibliographic Details
Main Authors: Vijai Williams, Muralidharan Jayashree, Karthi Nallasamy, Devi Dayal, Amit Rawat
Format: Article
Language:English
Published: BMC 2020-01-01
Series:Critical Care
Subjects:
Diabetes
Ketoacidosis
Pediatric
Fluids
Intensive care
Saline
Online Access:https://doi.org/10.1186/s13054-019-2683-3

Internet

https://doi.org/10.1186/s13054-019-2683-3

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