Identification of charged amino acids required for nuclear localization of human L1 ORF1 protein

Abstract Background Long Interspersed Element 1 (LINE-1) is a retrotransposon that is present in 500,000 copies in the human genome. Along with Alu and SVA elements, these three retrotransposons account for more than a third of the human genome sequence. These mobile elements are able to copy themse...

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Bibliographic Details
Main Authors: B. T. Freeman, M. Sokolowski, A. M. Roy-Engel, M. E. Smither, V. P. Belancio
Format: Article
Language:English
Published: BMC 2019-05-01
Series:Mobile DNA
Subjects:
L1
Online Access:http://link.springer.com/article/10.1186/s13100-019-0159-2