Development of a lateral flow recombinase polymerase amplification assay for rapid and visual detection of Cryptococcus neoformans/C. gattii in cerebral spinal fluid

Development of a lateral flow recombinase polymerase amplification assay for rapid and visual detection of Cryptococcus neoformans/C. gattii in cerebral spinal fluid

Abstract Background For definitive diagnosis of cryptococcal meningitis, Cryptococcus neoformans and/or C. gattii must be identified within cerebral spinal fluid from the patients. The traditional methods for detecting Cryptococcus spp. such as India ink staining and culture are not ideal. Although...

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Bibliographic Details
Main Authors: Qinglin Ma, Jilong Yao, Shixin Yuan, Houming Liu, Ning Wei, Jianming Zhang, Wanshui Shan
Format: Article
Language:English
Published: BMC 2019-02-01
Series:BMC Infectious Diseases
Subjects:
Cryptococcus neoformans
Cryptococcus gattii
Recombinase polymerase amplification
Lateral flow strips
Cerebral spinal fluid
Visual detection
Online Access:http://link.springer.com/article/10.1186/s12879-019-3744-6

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http://link.springer.com/article/10.1186/s12879-019-3744-6

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