Compound sophorae decoction enhances intestinal barrier function of dextran sodium sulfate induced colitis via regulating notch signaling pathway in mice

Compound sophorae decoction enhances intestinal barrier function of dextran sodium sulfate induced colitis via regulating notch signaling pathway in mice

Background: Compound sophorae decoction (CSD), a Chinese Herbal decoction, is frequently clinically prescribed for patients suffered from ulcerative colitis (UC) characterized by bloody diarrhea. Yet, the underlying mechanism about how this formulae works is remain elusive. Methods: In the present s...

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Bibliographic Details
Main Authors: Hui Wu, Qian-Yun Chen, Wen-Zhu Wang, Si Chu, Xing-Xing Liu, Yu-Jin Liu, Chen Tan, Feng Zhu, Shuang-Jiao Deng, Ya-Lan Dong, Ting Yu, Fei Gao, Hong-Xia He, Xue-Yuan Leng, Heng Fan
Format: Article
Language:English
Published: Elsevier 2021-01-01
Series:Biomedicine & Pharmacotherapy
Subjects:
Ulcerative colitis
Compound sophorae decoction
Barrier function
Intestinal epithelial cells
Mucus
Notch
Online Access:http://www.sciencedirect.com/science/article/pii/S075333222031129X

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http://www.sciencedirect.com/science/article/pii/S075333222031129X

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