Positive Selection of a Serine Residue in Bat IRF3 Confers Enhanced Antiviral Protection

Summary: Compared with other mammals, bats harbor more zoonotic viruses per species and do not demonstrate signs of disease on infection with these viruses. To counteract infections with viruses, bats have evolved enhanced mechanisms to limit virus replication and immunopathology. However, molecular...

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Bibliographic Details
Main Authors: Arinjay Banerjee, Xi Zhang, Alyssa Yip, Katharina S. Schulz, Aaron T. Irving, Dawn Bowdish, Brian Golding, Lin-Fa Wang, Karen Mossman
Format: Article
Language:English
Published: Elsevier 2020-03-01
Series:iScience
Online Access:http://www.sciencedirect.com/science/article/pii/S2589004220301425