Galectin-4 N-Terminal Domain: Binding Preferences Toward A and B Antigens With Different Peripheral Core Presentations

Galectin-4 N-Terminal Domain: Binding Preferences Toward A and B Antigens With Different Peripheral Core Presentations

The tandem-repeat Galectin-4 (Gal-4) contains two different domains covalently linked through a short flexible peptide. Both domains have been shown to bind preferentially to A and B histo blood group antigens with different affinities, although the binding details are not yet available. The biologi...

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Bibliographic Details
Main Authors: Jon I. Quintana, Sandra Delgado, Reyes Núñez-Franco, F. Javier Cañada, Gonzalo Jiménez-Osés, Jesús Jiménez-Barbero, Ana Ardá
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-04-01
Series:Frontiers in Chemistry
Subjects:
NMR
molecular recognition
galectin-4
blood type antigen
lectin—carbohydrate interaction
Online Access:https://www.frontiersin.org/articles/10.3389/fchem.2021.664097/full

Internet

https://www.frontiersin.org/articles/10.3389/fchem.2021.664097/full

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