Acute Toxoplasma Gondii Infection in Cats Induced Tissue-Specific Transcriptional Response Dominated by Immune Signatures

Acute Toxoplasma Gondii Infection in Cats Induced Tissue-Specific Transcriptional Response Dominated by Immune Signatures

RNA-sequencing was used to detect transcriptional changes in six tissues of cats, seven days after T. gondii infection. A total of 737 genes were differentially expressed (DEGs), of which 410 were up-regulated and 327 were down-regulated. The liver exhibited 151 DEGs, lung (149 DEGs), small intestin...

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Bibliographic Details
Main Authors: Wei Cong, Tania Dottorini, Faraz Khan, Richard D. Emes, Fu-Kai Zhang, Chun-Xue Zhou, Jun-Jun He, Xiao-Xuan Zhang, Hany M. Elsheikha, Xing-Quan Zhu
Format: Article
Language:English
Published: Frontiers Media S.A. 2018-10-01
Series:Frontiers in Immunology
Subjects:
Toxoplasma gondii
host-parasite interaction
transcriptome
differential gene expression
biomarkers
Online Access:https://www.frontiersin.org/article/10.3389/fimmu.2018.02403/full

Internet

https://www.frontiersin.org/article/10.3389/fimmu.2018.02403/full

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