Antigen pulsed CpG-ODN activated dendritic cells induce host-protective immune response by regulating the T regulatory cell functioning in Leishmania donovani-infected mice: critical role of CXCL10

Antigen pulsed CpG-ODN activated dendritic cells induce host-protective immune response by regulating the T regulatory cell functioning in Leishmania donovani-infected mice: critical role of CXCL10

Visceral leishmaniasis (VL), caused by Leishmania donovani, is a systemic infection of reticulo-endothelial system. There is currently no protective vaccine against VL and chemotherapy is increasingly limited due to appearance of drug resistance to first line drugs such as antimonials and amphoteric...

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Bibliographic Details
Main Authors: Saikat eMajumder, Amrita eBhattacharjee, Bidisha epaulchowdhury, Suchandra eBhattacharyya Majumdar, Subrata eMajumdar
Format: Article
Language:English
Published: Frontiers Media S.A. 2014-06-01
Series:Frontiers in Immunology
Subjects:
Leishmania
dendritic cell
Vaccine
T regulatory cells
CXCL10
Online Access:http://journal.frontiersin.org/Journal/10.3389/fimmu.2014.00261/full

Internet

http://journal.frontiersin.org/Journal/10.3389/fimmu.2014.00261/full

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