Hereditary diffuse gastric cancer therapeutic roadmap: current and novel approaches in a nutshell

Hereditary diffuse gastric cancer (HDGC) is a rare malignancy characterized by autosomal dominant inheritance of pathological variants of the CDH1 gene encoding E-cadherin, which is involved in cell–cell adhesion, maintenance of epithelial architecture, tumor suppression, and regulation of intracell...

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Bibliographic Details
Main Authors: Fadi E. El Rami, Hampartsoum B. Barsoumian, Gebran W. Khneizer
Format: Article
Language:English
Published: SAGE Publishing 2020-10-01
Series:Therapeutic Advances in Medical Oncology
Online Access:https://doi.org/10.1177/1758835920967238