A novel lipidomic strategy reveals plasma phospholipid signatures associated with respiratory disease severity in cystic fibrosis patients.

The aim of this study was to search for lipid signatures in blood plasma from cystic fibrosis (CF) patients using a novel MALDI-TOF-ClinProTools strategy, initially developed for protein analysis, and thin layer chromatography coupled to MALDI-TOF (TLC-MALDI). Samples from 33 CF patients and 18 heal...

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Main Authors: Ida Chiara Guerrera, Giuseppe Astarita, Jean-Philippe Jais, Dorota Sands, Anna Nowakowska, Julien Colas, Isabelle Sermet-Gaudelus, Martin Schuerenberg, Daniele Piomelli, Aleksander Edelman, Mario Ollero
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2009-11-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC2768907?pdf=render