Systematic profiling of alternative splicing in Helicobacter pylori-negative gastric cancer and their clinical significance

Abstract Background Alternative splicing (AS) may cause structural and functional variations in the protein to promote the proliferation of tumor cells. However, there is no comprehensive analysis of the clinical significance of AS in Helicobacter pylori-negative gastric cancer (HP − GC). Methods Th...

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Bibliographic Details
Main Authors: Chuan Liu, Chuan Hu, Zhi Li, Jing Feng, Jiale Huang, Bowen Yang, Ti Wen
Format: Article
Language:English
Published: BMC 2020-06-01
Series:Cancer Cell International
Subjects:
Online Access:http://link.springer.com/article/10.1186/s12935-020-01368-8