Sulfaphenazole Attenuates Myocardial Cell Apoptosis Accompanied With Cardiac Ischemia–Reperfusion by Suppressing the Expression of BimEL and Noxa

We previously reported the administration of a potent cytochrome P450 inhibitor, sulfaphenazole (SPZ), to suppress oxidative stress and the extension of myocardial infarct size in a rat model of cardiac ischemia–reperfusion (I/R). The aim of this study was to investigate the effects of SPZ on the my...

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Bibliographic Details
Main Authors: Yasuhiro Ishihara, Norio Shimamoto
Format: Article
Language:English
Published: Elsevier 2012-01-01
Series:Journal of Pharmacological Sciences
Online Access:http://www.sciencedirect.com/science/article/pii/S1347861319304955