Multiparametric analysis of anti-proliferative and apoptotic effects of gold nanoprisms on mouse and human primary and transformed cells, biodistribution and toxicity in vivo

Multiparametric analysis of anti-proliferative and apoptotic effects of gold nanoprisms on mouse and human primary and transformed cells, biodistribution and toxicity in vivo

Abstract Background The special physicochemical properties of gold nanoprisms make them very useful for biomedical applications including biosensing and cancer therapy. However, it is not clear how gold nanoprisms may affect cellular physiology including viability and other critical functions. We re...

Full description

Bibliographic Details
Main Authors: Marta Pérez-Hernández, María Moros, Grazyna Stepien, Pablo del Pino, Sebastián Menao, Marcelo de las Heras, Maykel Arias, Scott G. Mitchell, Beatriz Pelaz, Eva M. Gálvez, Jesús M. de la Fuente, Julián Pardo
Format: Article
Language:English
Published: BMC 2017-10-01
Series:Particle and Fibre Toxicology
Subjects:
Gold nanoprisms
Nanotoxicology
ROS generation
Mitochondrial membrane-potential
Biodistribution
In vivo
Online Access:http://link.springer.com/article/10.1186/s12989-017-0222-4

Internet

http://link.springer.com/article/10.1186/s12989-017-0222-4

Similar Items