Synthesis and In-silico Simulation of Some New Bis-thiazole Derivatives and Their Preliminary Antimicrobial Profile: Investigation of Hydrazonoyl Chloride Addition to Hydroxy-Functionalized Bis-carbazones

Synthesis and In-silico Simulation of Some New Bis-thiazole Derivatives and Their Preliminary Antimicrobial Profile: Investigation of Hydrazonoyl Chloride Addition to Hydroxy-Functionalized Bis-carbazones

Two new series of bis-thiazoles 6a-f and bis-thiazolones 9a-d were prepared via reacting bis-thiosemicarbazone 3 with hydrazonoyl chloride derivatives 4a-f and 7a-d, respectively, in dioxane under basic conditions. Another group of bis-thiazole derivatives 12a-h was prepared by reacting bis-thiosemi...

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Bibliographic Details
Main Authors: Refaie M. Kassab, Sobhi M. Gomha, Sami A. Al-Hussain, Ahmed S. Abo Dena, Marwa M. Abdel-Aziz, Magdi E.A. Zaki, Zeinab A. Muhammad
Format: Article
Language:English
Published: Elsevier 2021-11-01
Series:Arabian Journal of Chemistry
Subjects:
Carbazone
Hydrazonoyl chlorides
Bis-thiazoles
Antimicrobial
DFT
In-silico studies
Online Access:http://www.sciencedirect.com/science/article/pii/S1878535221004111

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http://www.sciencedirect.com/science/article/pii/S1878535221004111

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