3,5,6,7,8,3′,4′-Heptamethoxyflavone, a Citrus Polymethoxylated Flavone, Attenuates Inflammation in the Mouse Hippocampus

3,5,6,7,8,3′,4′-Heptamethoxyflavone, a Citrus Polymethoxylated Flavone, Attenuates Inflammation in the Mouse Hippocampus

Citrus polymethoxylated flavones (PMFs) have recently been shown to suppress inflammation in peripheral tissues. In the present study, we investigated the effects of 3,5,6,7,8,3′,4′-heptamethoxyflavone (HMF), one of the PMFs, on inflammation in the brain in vivo using mice injected intrahippocampall...

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Bibliographic Details
Main Authors: Satoshi Okuyama, Kazuhiro Miyoshi, Yuichi Tsumura, Yoshiaki Amakura, Morio Yoshimura, Takashi Yoshida, Mitsunari Nakajima, Yoshiko Furukawa
Format: Article
Language:English
Published: MDPI AG 2015-04-01
Series:Brain Sciences
Subjects:
3,5,6,7,8,3′,4′-heptamethoxyflavone
anti-inflammation
hippocampus
microglia
IL-1β
Online Access:http://www.mdpi.com/2076-3425/5/2/118

Internet

http://www.mdpi.com/2076-3425/5/2/118

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