Extracellular Vesicles Derived From Human Umbilical Cord Mesenchymal Stem Cells Protect Against DOX-Induced Heart Failure Through the miR-100-5p/NOX4 Pathway

Extracellular Vesicles Derived From Human Umbilical Cord Mesenchymal Stem Cells Protect Against DOX-Induced Heart Failure Through the miR-100-5p/NOX4 Pathway

The end result of a variety of cardiovascular diseases is heart failure. Heart failure patients’ morbidity and mortality rates are increasing year after year. Extracellular vesicles (EVs) derived from human umbilical cord mesenchymal stem cells (HucMSC-EVs) have recently been discovered to be an alt...

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Bibliographic Details
Main Authors: Zhenglong Zhong, Yuqing Tian, Xiaoming Luo, Jianjie Zou, Lin Wu, Julong Tian
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-08-01
Series:Frontiers in Bioengineering and Biotechnology
Subjects:
oxidative stress
miR-100-5p
NOX4
heart failure
human umbilical cord mesenchymal stem cells
extracellular vesicles
Online Access:https://www.frontiersin.org/articles/10.3389/fbioe.2021.703241/full

Internet

https://www.frontiersin.org/articles/10.3389/fbioe.2021.703241/full

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