Limited proteolysis of a disulfide-linked apoA-I dimer in reconstituted HDL

Limited proteolysis of a disulfide-linked apoA-I dimer in reconstituted HDL

The apolipoprotein A-IMilano (apoA-IM) is a molecular variant of apoA-I characterized by the Arg173“→Cys substitution, leading to the formation of homodimers A-IM/A-IM. Upon interaction with palmitoyloleoylphosphatidylcholine, A-IM/A-IM forms only two species of reconstituted HDL (rHDL) particles, w...

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Bibliographic Details
Main Authors: Laura Calabresi, Gabriella Tedeschi, Chiara Treu, Severino Ronchi, Debora Galbiati, Silvia Airoldi, Cesare R. Sirtori, Yves Marcel, Guido Franceschini
Format: Article
Language:English
Published: Elsevier 2001-06-01
Series:Journal of Lipid Research
Subjects:
limited proteolysis
protein conformation
apolipoprotein A-IMilano
Online Access:http://www.sciencedirect.com/science/article/pii/S0022227520316175

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http://www.sciencedirect.com/science/article/pii/S0022227520316175

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