Alzheimer’s disease Aβ assemblies mediating rapid disruption of synaptic plasticity and memory

Alzheimer’s disease Aβ assemblies mediating rapid disruption of synaptic plasticity and memory

<p>Abstract</p> <p>Alzheimer’s disease (AD) is characterized by episodic memory impairment that often precedes clinical diagnosis by many years. Probing the mechanisms of such impairment may provide much needed means of diagnosis and therapeutic intervention at an early, pre-dement...

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Bibliographic Details
Main Authors: Klyubin Igor, Cullen William K, Hu Neng-Wei, Rowan Michael J
Format: Article
Language:English
Published: BMC 2012-07-01
Series:Molecular Brain
Subjects:
Amyloidogenic proteins
Long-term potentiation
Long-term depression
Alzheimer’s disease
Neurodegenerative diseases
α-synuclein oligomers
PrP oligomers
Online Access:http://www.molecularbrain.com/content/5/1/25

Internet

http://www.molecularbrain.com/content/5/1/25

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