Peptidyl-Prolyl Cis/Trans Isomerase Pin1 and Alzheimer’s Disease

Alzheimer’s disease (AD) is the most common cause of dementia with cognitive decline. The neuropathology of AD is characterized by intracellular aggregation of neurofibrillary tangles consisting of hyperphosphorylated tau and extracellular deposition of senile plaques composed of beta-amyloid peptid...

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Bibliographic Details
Main Authors: Long Wang, Ying Zhou, Dongmei Chen, Tae Ho Lee
Format: Article
Language:English
Published: Frontiers Media S.A. 2020-05-01
Series:Frontiers in Cell and Developmental Biology
Subjects:
tau
Online Access:https://www.frontiersin.org/article/10.3389/fcell.2020.00355/full