Autoantibodies Recognizing Secondary NEcrotic Cells Promote Neutrophilic Phagocytosis and Identify Patients With Systemic Lupus Erythematosus

Autoantibodies Recognizing Secondary NEcrotic Cells Promote Neutrophilic Phagocytosis and Identify Patients With Systemic Lupus Erythematosus

Deficient clearance of apoptotic cells reportedly contributes to the etiopathogenesis of the autoimmune disease systemic lupus erythematosus (SLE). Based on this knowledge, we developed a highly specific and sensitive test for the detection of SLE autoantibodies (AAb) utilizing secondary NEcrotic ce...

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Bibliographic Details
Main Authors: Mona H. C. Biermann, Sebastian Boeltz, Elmar Pieterse, Jasmin Knopf, Jürgen Rech, Rostyslav Bilyy, Johan van der Vlag, Angela Tincani, Jörg H. W. Distler, Gerhard Krönke, Georg Andreas Schett, Martin Herrmann, Luis E. Muñoz
Format: Article
Language:English
Published: Frontiers Media S.A. 2018-05-01
Series:Frontiers in Immunology
Subjects:
systemic lupus erythematosus
secondary necrosis
autoimmunity
autoantibodies
inflammation
connective tissue diseases
Online Access:http://journal.frontiersin.org/article/10.3389/fimmu.2018.00989/full

Internet

http://journal.frontiersin.org/article/10.3389/fimmu.2018.00989/full

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