Defective interfering viral particles in acute dengue infections.

While much of the genetic variation in RNA viruses arises because of the error-prone nature of their RNA-dependent RNA polymerases, much larger changes may occur as a result of recombination. An extreme example of genetic change is found in defective interfering (DI) viral particles, where large sec...

Full description

Bibliographic Details
Main Authors: Dongsheng Li, William B Lott, Kym Lowry, Anita Jones, Hlaing Myat Thu, John Aaskov
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2011-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3084866?pdf=render