Modulation of cell sialoglycophenotype: a stylish mechanism adopted by Trypanosoma cruzi to ensure its persistence in the infected host

Trypanosoma cruzi, the etiological agent of Chagas disease exhibits multiple mechanisms to guarantee its establishment and persistence in the infected host. It has been well demonstrated that T. cruzi is not able to synthesize sialic acids (Sia). To acquire the monosaccharide, the parasite makes use...

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Main Authors: Leonardo eFreire-de-Lima, Leonardo Marques Fonseca, Vanessa Amil Silva, Kelli Monteiro Costa, Alexandre eMorrot, Celio Geraldo Freire-de-Lima, Jose Osvaldo Previato, Lucia eMendonça-Previato
Format: Article
Language:English
Published: Frontiers Media S.A. 2016-05-01
Series:Frontiers in Microbiology
Subjects:
Online Access:http://journal.frontiersin.org/Journal/10.3389/fmicb.2016.00698/full