RNA-Sequencing Analysis of 5' Capped RNAs Identifies Many New Differentially Expressed Genes in Acute Hepatitis C Virus Infection

RNA-Sequencing Analysis of 5' Capped RNAs Identifies Many New Differentially Expressed Genes in Acute Hepatitis C Virus Infection

We describe the first report of RNA sequencing of 5' capped (Pol II) RNAs isolated from acutely hepatitis C virus (HCV) infected Huh 7.5 cells that provides a general approach to identifying differentially expressed annotated and unannotated genes that participate in viral-host interactions. We...

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Bibliographic Details
Main Authors: Bret S. E. Heale, Shuanghu Liu, Don A. Delker, Neven Papic, Christopher I. Maxwell, Curt H. Hagedorn
Format: Article
Language:English
Published: MDPI AG 2012-04-01
Series:Viruses
Subjects:
HCV
JFH-1
RNA-seq
gene expression
next generation sequencing
5' cap
Huh 7.5
FUT1
KLHDC7B
Online Access:http://www.mdpi.com/1999-4915/4/4/581/

Internet

http://www.mdpi.com/1999-4915/4/4/581/

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