Generation and characterization of a Meflin-CreERT2 transgenic line for lineage tracing in white adipose tissue.

Generation and characterization of a Meflin-CreERT2 transgenic line for lineage tracing in white adipose tissue.

Meflin (Islr) expression has gained attention as a marker for mesenchymal stem cells, but its function remains largely unexplored. Here, we report the generation of Meflin-CreERT2 mice with CreERT2 inserted under the Meflin gene promoter to label Meflin-expressing cells genetically, thereby enabling...

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Bibliographic Details
Main Authors: Takahide Kuwano, Hironori Izumi, Muhammad Rahil Aslam, Yoshiko Igarashi, Muhammad Bilal, Ayumi Nishimura, Yoshiyuki Watanabe, Allah Nawaz, Tomonobu Kado, Koichi Ikuta, Seiji Yamamoto, Masakiyo Sasahara, Shiho Fujisaka, Kunimasa Yagi, Hisashi Mori, Kazuyuki Tobe
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2021-01-01
Series:PLoS ONE
Online Access:https://doi.org/10.1371/journal.pone.0248267

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https://doi.org/10.1371/journal.pone.0248267

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