Current concepts in the pathogenesis of primary biliary cirrhosis

Primary biliary cirrhosis (PBC) is an organ-specific autoimmune disease that predominantly affects women and is characterized by chronic, progressive destruction of small intrahepatic bile duct with portal inflammation and ultimately fibrosis, leading to liver failure in the absence of treatment. Th...

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Bibliographic Details
Main Authors: Phunchai Charatcharoenwitthaya, Keith D. Lindor
Format: Article
Language:English
Published: Elsevier 2005-07-01
Series:Annals of Hepatology
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S1665268119320617