Synthesis and anti-human immunodeficiency virus activity of substituted (-difluorophenyl)-linked-pyrimidines as potent non‐nucleoside reverse transcriptase inhibitors

With the worldwide number of human immunodeficiency virus positive patients stagnant and the increasing emergence of viral strains resistant to current treatment, the development of novel anti-human immunodeficiency virus drug candidates is a perpetual quest of medicinal chemists. Herein, we report...

Full description

Bibliographic Details
Main Authors: Lucie Čechová, Milan Dejmek, Ondřej Baszczyňski, David Šaman, Liping Gao, Eric Hu, George Stepan, Petr Jansa, Zlatko Janeba, Petr Šimon
Format: Article
Language:English
Published: SAGE Publishing 2019-02-01
Series:Antiviral Chemistry & Chemotherapy
Online Access:https://doi.org/10.1177/2040206619826265