Hypomethylation and Aberrant Expression of the Glioma Pathogenesis-Related 1 Gene in Wilms Tumors

Hypomethylation and Aberrant Expression of the Glioma Pathogenesis-Related 1 Gene in Wilms Tumors

Wilms tumors (WTs) have a complex etiology, displaying genetic and epigenetic changes, including loss of imprinting (LOI) and tumor suppressor gene silencing. To identify new regions of epigenetic perturbation in WTs, we screened kidney and tumor DNA using CpG island (CGI) tags associated with canc...

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Bibliographic Details
Main Authors: Laxmi Chilukamarri, Anne L. Hancock, Sally Malik, Joanna Zabkiewicz, Jenny A. Baker, Alexander Greenhough, Anthony R. Dallosso, Tim Hui-Ming Huang, Brigitte Royer-Pokora, Keith W. Brown, Karim Malik
Format: Article
Language:English
Published: Elsevier 2007-11-01
Series:Neoplasia: An International Journal for Oncology Research
Subjects:
Wilms tumor
epigenetics
hypomethylation
GLIPR1/RTVP-1
overexpression
Online Access:http://www.sciencedirect.com/science/article/pii/S147655860780025X

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http://www.sciencedirect.com/science/article/pii/S147655860780025X

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