Nef Secretion into Extracellular Vesicles or Exosomes Is Conserved across Human and Simian Immunodeficiency Viruses

Nef Secretion into Extracellular Vesicles or Exosomes Is Conserved across Human and Simian Immunodeficiency Viruses

Extracellular vesicles (EVs) or exosomes have been implicated in the pathophysiology of infections and cancer. The negative regulatory factor (Nef) encoded by simian immunodeficiency virus (SIV) and human immunodeficiency virus (HIV) plays a critical role in the progression to AIDS and impairs endos...

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Bibliographic Details
Main Authors: Ryan P. McNamara, Lindsey M. Costantini, T. Alix Myers, Blake Schouest, Nicholas J. Maness, Jack D. Griffith, Blossom A. Damania, Andrew G. MacLean, Dirk P. Dittmer, Vincent R. Racaniello
Format: Article
Language:English
Published: American Society for Microbiology 2018-02-01
Series:mBio
Online Access:http://mbio.asm.org/cgi/content/full/9/1/e02344-17

Internet

http://mbio.asm.org/cgi/content/full/9/1/e02344-17

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