Control of directionality of chromatin folding for the inter- and intra-domain contacts at the Tfap2c–Bmp7 locus

Control of directionality of chromatin folding for the inter- and intra-domain contacts at the Tfap2c–Bmp7 locus

Abstract Background Contact domains of chromatin serve as a fundamental unit to regulate action of enhancers for target genes. Looping between a pair of CCCTC-binding factor (CTCF)-binding sites in convergent orientations underlies the formation of contact domains, while those in divergent orientati...

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Bibliographic Details
Main Authors: Taro Tsujimura, Osamu Takase, Masahiro Yoshikawa, Etsuko Sano, Matsuhiko Hayashi, Tsuyoshi Takato, Atsushi Toyoda, Hideyuki Okano, Keiichi Hishikawa
Format: Article
Language:English
Published: BMC 2018-09-01
Series:Epigenetics & Chromatin
Subjects:
Chromatin conformation
Contact domains
Boundary
CTCF
cis interaction
Online Access:http://link.springer.com/article/10.1186/s13072-018-0221-1

Internet

http://link.springer.com/article/10.1186/s13072-018-0221-1

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