Reduced Intracellular c-di-GMP Content Increases Expression of Quorum Sensing-Regulated Genes in Pseudomonas aeruginosa

Reduced Intracellular c-di-GMP Content Increases Expression of Quorum Sensing-Regulated Genes in Pseudomonas aeruginosa

Cyclic-di-GMP (c-di-GMP) is an intracellular secondary messenger which controls the biofilm life cycle in many bacterial species. High intracellular c-di-GMP content enhances biofilm formation via the reduction of motility and production of biofilm matrix, while low c-di-GMP content in biofilm cells...

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Bibliographic Details
Main Authors: Song Lin Chua, Yang Liu, Yingying Li, Hui Jun Ting, Gurjeet S. Kohli, Zhao Cai, Pipob Suwanchaikasem, Kelvin Kau Kit Goh, Sean Pin Ng, Tim Tolker-Nielsen, Liang Yang, Michael Givskov
Format: Article
Language:English
Published: Frontiers Media S.A. 2017-10-01
Series:Frontiers in Cellular and Infection Microbiology
Subjects:
Pseudomonas aeruginosa
cyclic-di-GMP
quorum sensing
PQS
rhamnolipids
Online Access:http://journal.frontiersin.org/article/10.3389/fcimb.2017.00451/full

Internet

http://journal.frontiersin.org/article/10.3389/fcimb.2017.00451/full

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