T-cell populations and cytokine expression are impaired in thymus and spleen of protein malnourished BALB/c mice infected with Leishmania infantum.

Visceral leishmaniasis (VL) is a parasitic infectious disease that causes significant morbidity and mortality in the tropical and subtropical regions of the world. Although infections with visceralizing Leishmania may be asymptomatic, factors such as undernutrition increase the likelihood of progres...

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Main Authors: Sergio Cuervo-Escobar, Monica Losada-Barragán, Adriana Umaña-Pérez, Renato Porrozzi, Leonardo Saboia-Vahia, Luisa H M Miranda, Fernanda N Morgado, Rodrigo C Menezes, Myriam Sánchez-Gómez, Patricia Cuervo
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2014-01-01
Series:PLoS ONE
Online Access:https://doi.org/10.1371/journal.pone.0114584